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| Dosage | Package | Price per Dose | Price | |
|---|---|---|---|---|
| 1% | 5 tube | £7.74 | £45.54 £38.71 Best Price | |
| 1% | 4 tube | £9.11 | £42.86 £36.43 | |
| 1% | 3 tube | £10.63 | £37.50 £31.88 | |
| 1% | 2 tube | £12.14 | £28.57 £24.29 | |
| 5% | 5 tube | £18.98 | £111.63 £94.89 Popular | |
| 5% | 4 tube | £20.50 | £96.45 £81.98 | |
| 5% | 3 tube | £22.77 | £80.37 £68.32 | |
| 5% | 2 tube | £26.56 | £62.51 £53.13 |
Disclaimer: This information is for readers in the United Kingdom. It provides general guidance and is not a substitute for professional medical advice. Always follow the instructions given by your doctor or pharmacist and refer to the official product leaflet for Efudex.
Efudex is a topical cream that contains the active ingredient 5-fluorouracil (5-FU). It is used on the skin to treat certain conditions and lesions that are caused by abnormal skin cell growth. The medicine works locally on the skin where it is applied.
The cream is intended for external use only. It should be applied to the affected area as directed by your clinician. If you have any questions about why it has been prescribed for you, ask your doctor or pharmacist for clarification.
Efudex may require a prescription depending on local rules. In the United Kingdom, a healthcare professional will determine whether this treatment is appropriate for you. Always use the medicine exactly as prescribed and do not share your medicine with others.
If you are unsure about any ingredient in Efudex, or if you have had a reaction to similar medicines in the past, tell your clinician before starting treatment. Do not apply Efudex to areas of skin that are not affected unless advised to do so by a professional.
Efudex is used on the skin to treat actinic keratoses (AKs), which are sun-related rough patches or spots on the skin. In some cases, doctors may also use it for other superficial skin conditions as advised.
The medicine is applied only to the affected skin area. It should not be used on healthy skin unless instructed by your clinician. It is not a treatment for internal cancers.
Your doctor will decide how long to use Efudex and how often to apply it. It is important to follow their instructions and to attend follow-up visits as requested. If you are unsure about the treatment plan, contact your healthcare professional for clarification.
Efudex may be prescribed as part of a broader treatment plan. Always use it in combination with the guidance given by your clinician and the official leaflet that accompanies the medicine.
5-fluorouracil is a chemotherapy agent that interferes with the growth of rapidly dividing skin cells. By acting on abnormal cells in the treated area, it helps reduce or remove affected skin patches as part of the treatment plan.
As the medicine works, the treated skin commonly becomes inflamed. This can include redness, swelling, crusting or blistering in the area where Efudex was applied. These reactions are a known part of the local treatment response and should be discussed with your clinician if they become particularly uncomfortable.
The skin changes usually occur in the treated area and may extend to surrounding skin to some degree. After finishing the course, the skin typically heals and normal colour returns gradually. The exact course of healing can vary between individuals.
If you notice signs that worry you, such as fever, severe swelling, or signs of infection in the treated area, contact a healthcare professional promptly. Seek urgent medical help if you believe you have a serious reaction.
Your doctor or pharmacist will give you specific instructions on how to use Efudex. Use the cream exactly as prescribed and do not change the way you apply it without medical advice.
Before applying Efudex, gently wash and dry the treated area. Apply a thin layer of the cream to the affected skin as directed by your clinician. Avoid applying to healthy skin unless advised otherwise.
When applying Efudex, take care to keep the cream away from the eyes, mouth, and mucous membranes. Do not cover the treated area with a bandage or dressing unless your clinician specifically tells you to do so. After applying the cream, wash your hands unless they are the treated area.
Apply the medication at the frequency and for the duration recommended by your clinician. If you miss a dose, follow the guidance given by your doctor or pharmacist. Do not double-dose to make up for a missed application without medical advice.
Possible safety steps include avoiding the use of other skin products on the treated area unless advised, protecting the area from strong sunlight, and reporting any severe irritation to your clinician. If you are unsure about combining Efudex with other skin treatments, ask for professional guidance.
Avoid Efudex if you know you are allergic to 5-fluorouracil or any of the other ingredients in the cream. An allergy could cause a reaction such as itching, swelling, or a rash.
Do not apply Efudex to areas of skin that are broken, infected, or heavily irritated unless your clinician has advised otherwise. Avoid the treated area if instructed not to apply any more medication.
If you have had severe skin reactions to similar treatments in the past, discuss this with your clinician before starting Efudex. Share any other skin conditions you have or treatments you are receiving to ensure safe use.
During pregnancy or breastfeeding, talk to your doctor about the risks and benefits. The safety of Efudex in pregnancy or while breast-feeding has not been established in all situations, and alternatives may be considered.
The area treated with Efudex is typically more sensitive for a period during treatment. You may notice redness, warmth, or painful irritation. If these effects are bothersome or severe, contact your clinician for advice.
Exposure to sunlight can increase skin sensitivity while using Efudex. Take protective measures such as sunscreen, hats, and protective clothing as recommended by your clinician. Avoid tanning beds to reduce skin irritation.
Do not apply other skin products or medicines to the treated area unless your clinician has advised you to do so. Some products can worsen irritation or interact with Efudex. If you have concerns about using other products, ask your pharmacist.
If you notice signs of a serious reaction, such as swelling beyond the treated area, severe blistering, fever, or signs of infection, seek medical help promptly. If you think you may be having an allergic reaction, contact a healthcare professional right away.
Common side effects during Efudex treatment include redness, itching, burning, tenderness, and crusting of the treated skin. These reactions are expected as the medicine works on abnormal skin cells.
Some people may experience swelling, flaking skin, or changes in skin colour in the treated area. In rare cases, more widespread skin irritation or infection may occur, requiring medical attention.
Most skin reactions improve after finishing the course, but healing times vary. If the irritation or discomfort persists or worsens, contact your clinician for advice.
Allergic reactions to Efudex are uncommon but can occur. Seek medical help if you notice symptoms such as severe rash, swelling of the face or lips, or trouble breathing.
Efudex can interact with other medicines applied to the skin. Tell your doctor about all medicines you use on the skin, including over-the-counter products and herbal remedies. Some products may irritate the skin or affect how Efudex works.
Avoid using strong or fragranced skin products on the treated area unless advised by your clinician. If you are receiving other dermatological treatments, discuss timing and compatibility with your healthcare professional.
If you are using any other creams or ointments on or near the treated area, inform your clinician so they can provide tailored guidance about usage and potential interactions.
If you are pregnant or planning a pregnancy, talk to your doctor before starting Efudex. The safety of this medication during pregnancy has not been fully established in all situations. A clinician will weigh potential benefits against risks.
If you are currently breastfeeding, discuss with your healthcare professional whether Efudex is appropriate. They may advise on alternatives or timing related to breastfeeding.
Provide your clinician with a complete list of all medicines and supplements you take, as some products may influence treatment decisions during pregnancy or breastfeeding. Do not start or stop medications without professional guidance.
If you become pregnant during a course of treatment, inform your clinician promptly so that appropriate steps can be considered. Seek medical advice if you have any concerns about pregnancy while using Efudex.
Many people notice changes in the treated skin within a few weeks of starting therapy. The full course and healing may take several weeks, and timing can vary between individuals. Follow your clinician’s instructions and attend follow-up visits as advised.
Follow the guidance given by your clinician or the product leaflet. Do not double-apply to make up for a missed dose unless advised. If in doubt, contact a pharmacist or doctor for advice before applying more cream.
Tell your clinician about all medicines you use on the skin. Some products can interfere with Efudex or increase irritation. Do not start new skin treatments without medical advice during therapy.
Seek urgent medical help if you experience signs of a serious reaction such as rapid swelling, extensive blistering, fever, or signs of infection in the treated area. If you have trouble breathing or other signs of a severe allergic reaction, contact healthcare services promptly.
Yes. The treated skin is often more sensitive to sun exposure. Use sun protection and avoid intense sun or tanning while using Efudex and for a period after finishing treatment, as advised by your clinician.
Avoid shaving or waxing near the treated area unless your clinician tells you it is safe to do so. The skin can be more fragile during therapy and may react to hair removal methods.
Discuss pregnancy plans or breastfeeding with your clinician. The decision to use Efudex during pregnancy or breastfeeding depends on the specific clinical situation and alternatives may be considered.
The skin may stay red or irritated for some time after finishing Efudex. Healing finishes gradually and varies between people. If you have concerns, contact your clinician for advice.
Efudex may require a prescription depending on local rules. In the United Kingdom, a clinician will assess whether it is suitable for you. If you are buying online or from a pharmacy, follow their guidance and consult a pharmacist if you have any doubt.
Efudex should be used only on the skin areas specified by your doctor. Do not apply to other parts of the body unless advised. If you have questions about where to apply the cream, ask your clinician for clear instructions.
Official patient information for Efudex (5-fluorouracil) and related dermatology guidance provided by qualified healthcare professionals.
National health materials and leaflets used by UK clinicians to support patient understanding of actinic keratoses and topical chemotherapy agents.
General dermatology practice guidelines and standard patient safety information regarding topical chemotherapeutic agents and their skin reactions.
For individual advice, always refer to the product leaflet that accompanies Efudex and consult your GP, pharmacist, or dermatologist if you have any questions about your treatment.
14–21 days. Free from £151.83 .
5–9 days. £22.77
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−10% on all repeat orders.
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